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First, receiver operating characteristic curve (ROC) was used to calculate a cut-off value by comparing global MFIS score between pwPMS and pwRMS cohorts (Fig

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Numerous studies have documented a reduction in NAD + levels across various mouse tissues, including adipose (Yoshino et al., 2011), skeletal muscle (Frederick et al., 2015), liver (Trammell et al., 2016), and hypothalamus (Sasaki et al., 2014), concomitant with the development of obesity