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Obesity indication approval expanded GLP-1 addressable market by an estimated 10-15×: The US obesity drug market was approximately USD 2 billion in 2021 before Wegovy's approval

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Mice that received pre-BMT irradiation developed GVHD as expected, but neither minor antigen nor major antigen mismatch BMT was sufficient to cause GVHD in the absence of preconditioning