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[DOI] [PubMed] [Google Scholar] 21.Johnson DA, Andrews GK, Xu W, Johnson JA

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The most common cause of GH deficiency in childhood is believed to be caused by a lack of adequate stimulation of the pituitary gland by hypothalamic GHRH, which is why something like Ibutamoren which can systemically increase IGF-1 levels for 24 hours with a single oral dose is very promising for potential clinical use [R]