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FDA says its NIPP has “improved how data from pre-approval and surveillance inspections are evaluated and reported.” (FDA has been using these inspection protocols for certain sterile surveillance and pre-approval inspections since 2018.) Sites making “essential medicines” that protect the public against outbreaks of emerging diseases such as COVID-19 have high median site inspection scores (SIS), indicating a high rate of compliance with GMP
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Alterations in GSSG generation, recycling, and/or efflux have all been reported to be associated with correspondingly altered cell vulnerability to cell death in response to various cellular stresses
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