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presented the concept of adjuvant-induced autoimmune/inflammatory syndrome (ASIA), which describes a series of immune-mediated disorders that can be developed in genetically predisposed individuals ( A classic example of ASIA is the autoimmune complications of immune checkpoint inhibitor (ICI) therapy used in cancer treatment, known as immune-related adverse events (irAEs) ( The main side effects of ICI therapy may include chronic fatigue, unrefreshing sleep, sleep disturbances, cognitive problems and memory loss in up to 42% of cases ( Vaccine-triggered autoimmune syndromes fall within the scope of the ASIA syndrome (72–75)
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