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The first incorporates GSH into the mitochondria by inorganic phosphate exchange and the second by exchange of 2-oxoglutarate (Figures 2, 4)
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Regulatory Status Niagen has been successfully notified to the FDA as Generally Recognized as Safe (GRAS), and has been successfully reviewed by the FDA in 2015 and 2018 under its New Dietary Ingredient (NDI) notification program
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