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π Did you know reflux can actually change the cells in your esophagus if you ignore it?, β, β’ Most people think reflux = heartburn. But with silent reflux, you donβt always feel that burn. Instead, ...
doi: 10.1016/j.neuropharm.2008.05.008 31 FloresAJBartlettMJSoLYLaudeNDParentKLHeienMLet al
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Urolithin A activates the PTEN induced kinase 1 (PINK1)/Parkin RBR E3 ubiquitin protein ligase (PRKN) pathway, which tags dysfunctional mitochondria for degradation, while also stimulating mitochondrial biogenesis via the sirtuin 1 (SIRT1)/peroxisome proliferator-activated receptor gamma coactivator-1Ξ± (PGC-1Ξ±) signalling axis (Reference Ryu, Mouchiroud and Andreux15)
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