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FGF21 Agonists Hepatic lipid homeostasis is tightly controlled through the influences of insulin, free fatty acids, sterol regulated element-binding protein (SREBP), and nuclear receptors and associated regulatory molecules such as the liver X receptors (LXRs) and peroxisome proliferator-activated receptor α (PPARα), respectively
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In the early stages of tumor development, some authors consider this phenomenon positive
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