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There is a growing body of evidence linking increased oxidative stress to the pathogenesis of these disorders [132,133]

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Two-dimensional heteronuclear single-quantum correlation experiments were run on each sample to confirm the assignment of each metabolite (16 averages, relaxation delay 3s, 256 points in 2 nd dimension, SW 6500 Hz for 1 H, SW 20800 Hz for 13 C)