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Protein expression was induced by addition of 0.1 mM isopropyl b-D-1-thiogalactopyranoside (IPTG)

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Moreover, NFκB orchestrates the appearance of other molecular mediators that enable cellular adhesion (such as intercellular and vascular cell adhesion molecule 1 (ICAM-1 and VCAM) and, monocyte chemoattractant protein-1 (MCP-1)), as well as prothrombotic and pro-coagulant effects (such as plasminogen activator inhibitor-1 (PAI-1, which counteracts the physiological anti-coagulant tissue plasminogen activator (tPA)) [112,116]