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Because Wnt/ β-catenin signalling plays an important role in the aetiology of non-tumour diseases, small-molecule drugs targeting the Wnt/β-catenin signalling pathway have shown unique advantages in the treatment of these non-tumour diseases

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In a clinically relevant model of global ischemia after canine cardiac arrest, treatment with ALCAR reduced the amount of protein carbonyls which are formed after oxidative stress in brain [104]