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Areas of Interest Epitalon has been studied in relation to: Telomerase activity and telomere preservation Cellular aging and longevity markers Oxidative stress and DNA protection Pineal gland function and circadian rhythm Mitochondrial energy signaling Immune system support Read more about how this peptide works in our Epitalon benefits guide (update slug to match live blog URL)
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It is believed, however, that inhibition of MAO-A is necessary for antidepressant effects.24,25 The mechanism of available therapies for MDD is based on the principle of increasing synaptic availability of serotonin, norepinephrine, and/or dopamine—the monoamine neurotransmitters.26,27 The MAOIs inhibit the MAO enzyme, thereby allowing serotonin, norepinephrine, and dopamine to accumulate in the synapse.27,28 The MAO-A isoenzyme metabolizes serotonin, norepinephrine, and dopamine, while MAO-B primarily metabolizes dopamine