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Phase 2 trials demonstrated that patients completing 24 weeks of empatic360 (bupropion SR 360 mg/zonisamide SR 360 mg) and empatic-120 (bupropion 360 mg/zonisamide 120 mg) therapy attained a significant weight loss as compared to placebo (9.9%, 7.7% vs

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The basis of the method is the classical Newton equation of motion: where F i ( t ) is the force acting on atom i at time t , m i is the mass of the i -th atom, and a i ( t ) is the acceleration of atom i at time t

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