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Studies show that AMPK activates PGC-1α specifically through SIRT1, which requires NAD+ for deacetylation [3]
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Assessment of other variables Data on demographic characteristics (age, sex, ethnicity and educational level), lifestyle factors (smoking, alcohol consumption, and physical labor level), history of disease (supine hypertension and diabetes), and medication history were collected by face-to-face interviews with a standardized questionnaire
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