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As potent activators of PPARα ( In vitro experiments using palmitic acid-treated HepG2 cells further revealed that 14,15-EET inhibited the NF-κB/JNK signaling pathway, decreased malondialdehyde (MDA) levels, and enhanced antioxidant enzyme activities, including superoxide dismutase, catalase, and glutathione peroxidase ( Materials and methods Materials Standard chow diet (choline-sufficient, amino acid-defined, Cat # TP 1R810) and CDAA diet (Cat # TP 1R800) were procured from Trophic Animal Feed High-Tech Company, China