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Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15

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As mentioned, activation of the kynurenine pathway diverts tryptophan metabolism away from serotonin synthesis, while the resulting metabolites, such as quinolinic acid, an NMDA receptor agonist, and kynurenic acid, an NMDA and nicotinic receptor antagonist, alter glutamatergic signaling [276]

Glutathione peroxidase (GPX) represents an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage