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Other relevant factors include: Pre-existing conditions: Anaemia, hypothyroidism, sleep apnoea, and depression can all independently cause fatigue and may compound drug-related tiredness, making it harder to distinguish the cause
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You need to inform your doctor about the following side effects as soon as possible : Allergic reactions like skin rash, itching, hives, face, lips, or tongue swell (it can be avoided by a skin test before the injection) Fluid Retention and swelling in various parts of the body Breathing problems Breast enlargement Enlargement of penis and testes Ovarian hyperstimulation syndrome (OHSS), in which the ovaries become swollen and painful