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GHK-Cu is found naturally in human blood plasma, saliva, and urine, with plasma concentrations declining significantly with age — from approximately 200 ng/mL in young adults to around 80 ng/mL in those over 60

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(E–H) Concentrations of AA (E), AdA (F), Lin (G), and FFA (C22:6) (H) (n = 6 for each group)