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1 The agency reviewed the peptides for specific indications, Bpc-157 for ulcerative colitis, Kpv for wound healing and inflammatory conditions, Tb-500 for wound healing, and Mots-c for obesity and osteoporosis
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Latent activation of TGF-β signaling can occur through metalloprotease-dependent cleavage of LAP or LTBP or disruption of LAP-RGD interaction with integrins [163,164,165,166]
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