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For instance, beside the genetic models there are 21 additional models of AD tested in vivo that range from metal ion toxicity models such as aluminum-based and copper sulfate/cholesterol-based methods, immunological methods such as the IgG-saporin model, and neurotoxin models using colchicine or scopolamine

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It has been studied for decades in Russian neuroscience literature as a nootropic and neuroprotective research compound acting largely through BDNF and NGF modulation