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These initial findings have been confirmed in several other prospective, controlled studies in blood [9,10,11,12] and brain samples [13,14,15], and a meta-analysis has confirmed the consistency of these findings across multiple studies and multiple laboratories [5]
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Size:2 Grams
Statistical analysis A sample size of 300 participants provided an effective power of at least 96% for the two co-primary endpoints, and at least 43% for all confirmatory secondary endpoints, which were tested in a predefined hierarchical order (Supplementary Table 4)
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