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It is present ubiquitously, being most abundantly expressed in the liver (Chia et al., 2010) and is composed of a large extracellular domain involved in GH binding and GHR dimerization, a single transmembrane domain that anchors the receptor to the cell surface and an intracellular domain involved in GH signaling

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Maes M, Kubera M, Uytterhoeven M, Vrydags N, Bosmans E