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5-Amino-1MQ is studied for its proposed NNMT inhibition properties, with downstream research interest in NAD+ pathway and SIRT1 signalling modulation, while Methylene Blue is studied for distinct redox and electron-transfer properties relevant to mitochondrial pathway research

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Protein concentrations in 3D culture supernatant derived from Lu99 cells cultured at a cell density of 2×106 cells/ml (Lu99 supernatant) were determined using the Bradford method

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