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The above multicomponents target multiple pathological aspects such as lipid metabolism, inflammation, OS and fibrosis through synergistic effects, providing a material basis for the multi-targeting properties of ginseng in the treatment of NAFLD

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Recent highlight research indicates that in a murine model of nonalcoholic steatohepatitis (NASH) induced by a choline-deficient and ethionine-supplemented [25] diet, the administration of Trolox, a vitamin E analogue, has significantly decreased the levels of serum hepatic injury markers, attenuated the count of necrotic cells staining positively for specific biomarkers, and mitigated inflammatory responses [179]