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Importantly, upon re-expression of IFFO1 in IFFO1 −/− cells, the binding of Cdc42 to IQGAP3 was observed to decrease in a manner that was dependent on the amount of IFFO1 (Fig

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It exists naturally in human plasma, saliva, and urine — with plasma concentrations averaging ~200 ng/mL at age 20 but declining to ~80 ng/mL by age 60