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Similarly, obesity is defined as a BMI of ≥ 30 in most trials, except for SURMOUNT‐CN, where obesity is defined as a BMI of ≥ 28, and in the Japanese cohort of the SURMOUNT‐OSA trial, where a BMI of ≥ 27 defines obesity [18, 19]

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Consequently, NF-κB activity plays a central role in the inflammatory processes that manifest in chronic disease [43]