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This may have many benefits for detoxification and health but unlike drinking coffee, which is absorbed through the digestive tract, this method bypasses digestion and allows the caffeine to be absorbed directly into the bloodstream to stimulate the liver This unique route of absorption is what makes coffee enemas so effective for detoxification

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Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro