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Administration of Epigallocatechin Gallate (EGCG, 40 mg/kg for 1 month) could protect rats treated with NaF (25 mg/kg) by enhancing antioxidant levels (SOD, CAT, GPx, GST) and decreasing the expression of apoptosis and inflammation-related genes such as Bad, Cyt-c, Caspase-3, IL-1β, TNF-α, and COX-2 [64]

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doi:10.3104/reports.134 Introduction Individuals with Down syndrome seem to have an accelerated process of ageing (Carmeliet, David & Cassiman, 1991