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233,234 Scientists demonstrated downregulation of histone Kla enhanced the sensitivity of CRC cells to bevacizumab treatment in cell-based xenografts, patient-derived xenografts and patient-derived organoids models, which further broadens the role of Kla in antiangiogenic therapy

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doi: 10.1186/s40168-019-0654-1 192 TripathiA.DebeliusJ.BrennerD