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This did not make these peptides illegal to possess for research purposes, but it did eliminate the most quality-controlled supply channel for many users

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It is of note that pathogenic mutations in the SH2 domain of a number of cytoplasmic signaling peptides, including STAT1, have been associated with immuno-deficiencies, but none, except STAT5b, has been associated with severe growth retardation and IGF-I deficiency