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Given that FXS is a monogenic cause of ASD, these findings highlight both the challenges of translating GABAergic modulation into broad clinical efficacy and the importance of patient stratification in future trials of targeted therapies for neurodevelopmental disorders (152)

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It’s thought that by putting the brakes on NNMT, 5-Amino-1MQ could influence fundamental metabolic pathways linked to everything from body weight to the aging process itself