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Similarly, TRAIL binding to DR4 or DR5 recruits FADD and activates caspase-8/10, triggering downstream apoptotic events (Shakibaei et al., 2005)

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FUTURE DIRECTIONS & EMERGING TECHNOLOGIES Potential areas for future research and development Challenges for Induced Pluripotent Stem Cells-Derived Induced EC: Lineage Subtypes, Tissue Specificity, and Functional Validation Since induced pluripotent stem cells (iPSCs) were generated by Yamanaka et al