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423,424 The finite time step utilized to solve the Newton equations of motion, on the order of (1–2) × 10 –15 s, imposed by a full atomistic representation of the molecular assembly, has severe limitations on both the size- and time-scales explored by the simulations, notwithstanding the continuous increase of the available computational resources

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The calculator removes that ambiguity by computing the dose in milligrams from the IU value and the concentration