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Besides, there was a cardiac and hepatic histological evaluation after hematoxylin and eosin, and Masson staining, as well as immunohistochemistry measurement of caspase 3, nuclear factor kappa B (NF-κB) and inducible nitric oxide synthase (iNOS)

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MDM reprogramming in the tumor microenvironment MDMs are recruited to glioma during tumorigenesis and represent one-third of the infiltrating myeloid cells in the tumor microenvironment at the late stage [126]